I-C180SE CO2 Incubator | Inkampani yoNyango lweeSeli eShanghai​

I-C180SE 140°C High Heat Sterilization CO2 Incubator yethu itshintshe indlela esebenza ngayo inkcubeko yeeseli kwinkampani ephambili yonyango lweeseli eseShanghai egxile kwi-CAR-T kunye nonyango lweeseli ze-stem. Yenzelwe ukusetyenziswa okunobuthathaka kungcoliseko, i-C180SE's ​​full-chamber 140°C dry heat sterilization isuse umngcipheko we-biofilm phakathi kweebhetshi ezibalulekileyo zokwanda kweeseli zomzimba, ifikelela kwinqanaba le-99.999% lokubulala iintsholongwane kwiiyure ezi-3 kuphela.

Ilebhu yayifuna ulawulo lokufuma oluhambelana ne-GMP​ kwiinkcubeko ze-iPSC (induced pluripotent stem cell) ezinobuthathaka. Ulawulo lokufuma oluphindwe kabini lwe-C180SE lugcine i-95% RH (±2%) kwi-37°C ngelixa luthintela ukufuma—impumelelo ngexesha leenkqubo zokwahlulahlula zeentsuku ezingama-21. Ukujikeleza komoya okuhluziweyo yi-HEPA​​ kunciphise ungcoliseko lwe-fungus spore nge-98% xa kuthelekiswa ne-incubators eziqhelekileyo, njengoko kuqinisekisiwe kwimveliso ye-CD34+ hematopoietic stem cell.

Abaphandi bagxininise ukubaluleka kokubuyiselwa ngokukhawuleza emva kokubulala iintsholongwane: igumbi lifikelele kwinqanaba elifanelekileyo le-CO2 (5%) kwimizuzu emi-5, nto leyo evumela ukuqaliswa kwakhona kwangolo suku lunye kokudluliselwa kwevektha yeCAR-T enobukrelekrele bexesha. Imo yobusuku yokonga amandla inciphise ukusetyenziswa kwamandla ngama-40% ngaphandle kokubeka emngciphekweni uzinzo lobushushu, nto leyo ehambelana neemfuno zemveliso yesikhungo iiyure ezingama-24 ngosuku, iintsuku ezisixhenxe ngeveki.