Zoo siab rau RADOBIO Incubator Shaker rau kev pab CAS pab pawg tshawb fawb luam tawm hauv Xwm thiab Kev Tshawb Fawb

Thaum Lub Plaub Hlis 3, 2024,YiXiao Zhang's Labntawm Lub Chaw Sib Tshuam ntawm Biology thiab Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (SIOC), koom tes nrogCharles Cox lub chaw kuaj mobntawm Vitor Chang Heart Institute, Australia, thiabBen Corry lub chaw kuaj mobntawm Australian National University (ANU), tau luam tawm ib tsab xov xwm hauvXwmhu ua Mechanical activation qhib lub qhov lipid-lined hauv OSCA ion channels. Los ntawm kev sib sau ua ke OSCA proteins rau hauv nanophospholipid disks thiab liposomes los ua kom pom qhov chaw ib puag ncig mechanical, peb-dimensional conformation ntawm lub xeev activation ntawm OSCA proteins tau raug ntes, lub molecular mechanism ntawm lawv cov mechanical activation tau elucidated, thiab ib daim ntawv tshiab ntawm ion pore composition nrog phospholipid arrangement tau raug tshawb pom.

Tsab xov xwm hais tias ib qhoHerocell C1 CO2 incubator shakertsim los ntawmRADOBIOtau siv rau hauv kev sim.

Txuas mus rau tsab xov xwm thawj: https://www.nature.com/articles/s41586-024-07256-9

Rov qab rau lub Yim Hli 18, 2023,Charles Cox lub chaw kuaj mobntawm Victor Chang Heart Institute hauv tebchaws Australia thiabYiXiao Zhang's Labntawm Lub Chaw rau Kev Sib tshuam ntawm Biological thiab Chemical ntawm Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (SIOC), tau luam tawm ib tsab xov xwm hauvKev Tshawb Fawbhu ua MyoD-tsev neeg inhibitor proteins ua haujlwm ua cov subunits pabcuam ntawm Piezo channels. subunits ntawm Piezo channels. Tsab xov xwm kuj hais tias Herocell C1 all-purpose carbon dioxide incubator tsim los ntawm Rundle Biologicals tau siv rau hauv lawv cov kev sim. (Yog xav paub ntxiv, saib BioArt: Science 丨Charles Cox/Zhang Xiaoyi pab pawg pom MDFIC yog Piezo auxiliary subunit koom nrog kev tswj hwm mechanically gated)

Qhov txuas thawj: https://www.science.org/doi/10.1126/science.adh8190

 
Pab txhawb kev tshawb fawb txog kev tshawb fawb yooj yim, thev naus laus zis kom paub txog qhov zoo nkauj ntawm lub neej. Nws yeej ib txwm yog lub hom phiaj ntawm Radobio. Niaj hnub no, peb rov qab txaus siab rau lub hom phiaj no! Ua ib yam khoom tseem ceeb ntawm Radobio, Herocell C1 CO2 Incubator Shaker tau muab kev txhawb nqa zoo rau cov kws tshawb fawb nrog nws cov kev ua tau zoo heev thiab kev ua haujlwm ruaj khov. Peb zoo siab uas tau pab YiXiao Zhang's Lab ua qhov kev tshawb fawb tseem ceeb hauv lawv txoj kev tshawb fawb.

Qhov zoo nkauj ntawm thev naus laus zis yog nws lub peev xwm los coj lub neej zoo dua thiab kev noj qab haus huv rau tib neeg. Qhov kev tshawb pom los ntawm Zhang's Lab yog qhov piv txwv zoo tshaj plaws ntawm qhov zoo nkauj ntawm lub neej ua tau los ntawm kev tshawb fawb thiab thev naus laus zis. Cia peb tos ntsoov rau qhov kev ua tiav no pab txhawb rau kev noj qab haus huv ntawm ntau tus neeg.