03.Ogasiti 2023 | Msonkhano wa chitukuko cha njira zopangira mankhwala a biopharmaceutical

Msonkhano wa 2023 wa chitukuko cha biopharmaceutical bioprocess,radobio amagwira ntchito ngati wogulitsa maselo a biopharmaceutical.

Mwachikhalidwe, sayansi ya zamoyo ya labotale yakhala ntchito yaying'ono; mitsempha yotukula minofu nthawi zambiri siikula kuposa chikhato cha dzanja la woyesa, kuchuluka kwake kumayesedwa mu "milliliters," ndipo kuyeretsa mapuloteni kumaonedwa ngati kopambana ngati kumapereka ma microgram ochepa. Chifukwa cha kuyang'ana kwambiri pa kafukufuku womasulira, sayansi ya kapangidwe ka thupi ndi mankhwala obwezeretsa, asayansi ambiri akuyamba kuyang'ana "chithunzi chachikulu". Kaya akuyesera kuyeretsa magalamu ochepa a mapuloteni kuti ayesere kristalo kapena kuyesa kuthekera kopanga jini yatsopano kukhala mankhwala atsopano, ofufuzawa posakhalitsa amadzipeza akuganizira zovuta za chikhalidwe cha maselo akuluakulu.

Chifukwa cha zomwe makampani opanga zamoyo akwaniritsa, kukula kwa maselo m'njira yolunjika kwakhala njira yabwino kwambiri. "Mundawu wayamba kale kufalikira pamene zinthu zambiri zikubwera, kuyambira ma flask a 100 ml okhala ndi ma shakers mpaka ma bioreactor culture a 1,000 L, ndipo mankhwala amatha kupangidwa m'maselo a nyama zoyamwitsa kwambiri."

Radobio ikhoza kupereka zinthu zabwino kwambiri zogwedeza kuti zigwiritsidwe ntchito popanga maselo osungunulira, ndipo pamsonkhano uno, chinthu chatsopano chogwedeza CS345X chawonetsedwa, chomwe chili ndi ubwino wotsatira:
❏ Ma amplitude angapo osinthika kuti agwirizane ndi zosowa zosiyanasiyana za chitukuko cha maselo.
▸ 12.5/25/50mm yosinthika kukula, munthu akhoza kukwaniritsa bwino mayeso osiyanasiyana a chitukuko cha maselo, popanda kufunikira kugula zida zingapo pazosowa zosiyanasiyana zoyesera, zomwe zimapulumutsa ogwiritsa ntchito ndalama zambiri.
❏ Liwiro lalikulu, liwiro lochepa losalala komanso liwiro lokhazikika.
▸ Ukadaulo wapadera komanso watsopano wa ma bearing umakulitsanso kuchuluka kwa ma bearing control, komwe kumatha kukwaniritsa kuchuluka kwa ma bearing control a liwiro la 1 ~ 370rpm, kupereka chitsimikizo chogwira ntchito chokwaniritsa zosowa zosiyanasiyana zoyesera.
❏ Kutsegula chitseko chokwera mmwamba kumasunga malo ndipo kumapereka mwayi woti anthu aziona zomera.
▸ Kutsegula chitseko chokwera mmwamba kumapewa malo otseguka ndi chitseko chakunja, ndipo kumapereka mwayi wofikira mosavuta ku zikhalidwe.
❏ Ntchito yowongolera chinyezi yosankha imatha kulamulira chinyezi mpaka 90%rh
▸ Gawo lowongolera chinyezi lomangidwa mkati mwa Rindo limatsimikizira kuwongolera chinyezi molondola komanso kodalirika ndi kukhazikika kwa ±2% rh
❏ Choyendetsa maginito kuti chigwire ntchito bwino, chisagwiritse ntchito mphamvu zambiri, chiteteze chilengedwe komanso chisawononge mphamvu.
▸ Palibe chifukwa chomangira malamba, kuchepetsa chiopsezo cha kuipitsidwa chifukwa cha kutentha kwa kumbuyo chifukwa cha kukangana kwa lamba pa kutentha kwa incubation ndi tinthu tomwe timawonongeka.